全文获取类型
收费全文 | 203篇 |
免费 | 12篇 |
国内免费 | 17篇 |
出版年
2022年 | 2篇 |
2021年 | 2篇 |
2020年 | 4篇 |
2019年 | 2篇 |
2018年 | 2篇 |
2016年 | 6篇 |
2015年 | 4篇 |
2014年 | 8篇 |
2013年 | 8篇 |
2012年 | 9篇 |
2011年 | 14篇 |
2010年 | 8篇 |
2009年 | 5篇 |
2008年 | 5篇 |
2007年 | 11篇 |
2006年 | 9篇 |
2005年 | 6篇 |
2004年 | 8篇 |
2003年 | 8篇 |
2002年 | 6篇 |
2001年 | 6篇 |
2000年 | 3篇 |
1999年 | 3篇 |
1998年 | 5篇 |
1997年 | 9篇 |
1996年 | 3篇 |
1995年 | 6篇 |
1994年 | 4篇 |
1993年 | 6篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 4篇 |
1989年 | 5篇 |
1988年 | 4篇 |
1987年 | 6篇 |
1986年 | 2篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1980年 | 4篇 |
1979年 | 1篇 |
1977年 | 4篇 |
1976年 | 1篇 |
1975年 | 3篇 |
1973年 | 2篇 |
1972年 | 5篇 |
1971年 | 2篇 |
1967年 | 1篇 |
1956年 | 1篇 |
排序方式: 共有232条查询结果,搜索用时 698 毫秒
21.
22.
S.D. HA K.G. MACIOROWSKI S.C. RICKE 《Journal of Rapid Methods and Automation in Microbiology》1997,5(1):75-85
This study was designed to evaluate the effect of ethyl alcohol as a potential treatment for reduction of Salmonella populations in poultry feed. Growth rate of S. typhimurium in tryptic soy broth was significantly reduced by addition of greater than 0.3% volume/volume of ethyl alcohol and growth was completely inhibited by addition of 5% ethyl alcohol. Ethyl alcohol concentrations of 20% volume/weight and greater significantly reduced initial S.typhimurium populations in poultry feed (for 20% treated, 2.31 ± 0.31 vs 3.39 ± 0.29 for untreated; P < 0.05). When feed treatment was administered either before or after inoculation of S. typhimurium with 60% ethyl alcohol or 0.04% buffered propionic acid, populations in feeds treated after inoculation were decreased to a nondetection level (< 1.0 log10 CFU/g) by ethyl alcohol treatment but not by other treatments. Ethyl alcohol treatment may have the potential for reducing Salmonella spp. contamination in poultry feed. 相似文献
23.
24.
25.
二甲基亚砜毒性研究 总被引:1,自引:0,他引:1
二甲基亚砜(Dimethyl sulfoxide DMSO)是一种含硫有机化合物,被誉为"万能溶剂",广泛用作溶剂和反应试剂。在医药工业中,DMSO可直接用作某些药物的原料及载体。DMSO本身有消炎止痛,利尿,镇静等作用,亦誉为"万灵药",常作为止痛药物的活性组分添加于药物之中。DMSO也是一种渗透性保护剂,能够降低细胞冰点,减少冰晶的形成,减轻自由基对细胞损害,改变生物膜对电解质、药物、毒物和代谢产物的通透性。DMSO作为组蛋白去乙酰化酶抑制剂(Histone Deacetylases-inhibitor HDACi)的一种,同样具有恢复组蛋白的乙酰化与去乙酰化平衡,抑制细胞程序性死亡,修复DNA双螺旋结构,抗放射性损伤,抗炎症反应及抗癌作用。鉴于其应用广泛,本文就其物理特性及毒性研究做一综述。 相似文献
26.
27.
M Dowsett R C Stein R C Coombes 《The Journal of steroid biochemistry and molecular biology》1992,43(1-3):155-159
Aromatase inhibition in postmenopausal women causes a marked fall in the plasma levels of oestrogens and is an effective treatment for breast cancer, however, trials with aminoglutethimide found that this aromatase inhibitor was ineffective in suppressing plasma oestrogen levels in premenopausal breast cancer patients. We found that the more potent inhibitor, 4-hydroxyandrostenedione (4-OHA), which can suppress oestrogen synthesis in rodents and non-human primates with intact ovarian function, was also unsuccessful as an oestrogen suppressant in premenopausal women at its maximum tolerated dose (500 mg/week i.m.). GnRH agonists are effective suppressants of ovarian oestrogen synthesis but oestrogen production from peripheral sites is unaffected. Our studies of a combination of the GnRH agonist goserelin and 4-OHA demonstrated that the combination caused greater oestrogen suppression than goserelin alone and led to objective clinical response in 4/6 breast cancer patients after their relapse from treatment with goserelin as a single agent. The combination of a GnRH agonist and an aromatase inhibitor should be subjected to clinical trials. 相似文献
28.
CYCLOHEXIMIDE AS A MEDIA AMENDMENT FOR ENUMERATING BACTERIAL POPULATIONS IN ANIMAL FEEDS 总被引:1,自引:0,他引:1
S.D. HA S.D. PILLAI K.G. MACIOROWSKI S.C. RICKE 《Journal of Rapid Methods and Automation in Microbiology》1995,4(2):95-105
The present study was designed to evaluate cycloheximide as a potential media amendment for differential bacterial and fungal enumeration of animal feeds. The objectives of this study were to determine the effect of cycloheximide on bacterial growth rates and to evaluate its efficacy for the reduction of indigenous spreading fungi when enumerating bacterial populations in three types of feeds and after short or long-term storage. Escherichia coli, Bacillus cereus, Staphylococcus aureus, Listeria monocytogenes and Pseudomonas fluorescens were grown in tryptic soy broth containing cycloheximide to determine its effect on bacterial specific growth rates. Growth rates of B. cereus and S. aureus were significantly decreased by the addition of 600 and 1000 mg/L cycloheximide respectively, but other pure cultures were not significantly influenced by cycloheximide addition. Intrinsic bacterial populations from feed were not significantly affected by cycloheximide additions at concentrations from 10 to 300 mg/L, but the indigenous spreading molds from feeds were significantly decreased by these cycloheximide concentrations and were decreased below detection levels by 300 mg/L of cycloheximide. The addition of 300 mg/L of cycloheximide effectively eliminates fungal growth for accurate enumeration of bacterial populations in feeds. 相似文献
29.
Dr J Rogers A B Dowsett C W Keevil 《Journal of industrial microbiology & biotechnology》1995,15(4):377-383
A three-stage chemostat containing a mixed consortium of microorganisms, includingLegionella pneumophila, was used to determine the suitability of a silver-containing paint to control biofouling in water systems. The paint was efficient in controlling total surface colonisation by heterotrophic microorganisms and growth of the pathogen over a 2-week period. Biodiversity was limited in the presence of the silver paint and this was thought to help controlL. pneumophila numbers. Glass control tiles suspended alongside the silver painted tiles also had reduced colonisation for the 2-week period, suggesting that low levels of silver leached from the paint surface. This loss of silver was confirmed since the inhibition of biofouling and inclusion of the pathogen was not maintained after the 2-week period. Although this paint was unsuitable for controlling biofouling over extended time periods, the data suggest that a reformulated paint or electrochemical method of introducing silver ions may be successful. 相似文献
30.
S.D. HA K.G. MACIOROWSKI Y.M. KWON S.C. RICKE 《Journal of Rapid Methods and Automation in Microbiology》1997,5(4):309-319
The present study was designed to compare ethyl alcohol with buffered propionic acid feed treatment on the survival of indigenous poultry feed bacteria and fungi. The aerobic bacterial poultry feed populations were not substantially reduced by either ethyl alcohol or buffered propionic acid treatments. Likewise, indigenous poultry feed fungal populations also were not markedly reduced by buffered propionic acid treatment of the feed but fungal poultry feed populations exposed to ethyl alcohol treatments were significantly lower (P<0.05) than fungal populations recovered from either control and buffered propionic acid treated feeds. Ethyl alcohol treatment may have potential for reducing fungal contamination in poultry feed. 相似文献